Methods for treating acute acoustic trauma
US8420595B2 · kind B2 · utility
4Cited by
4References
34Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 25, 2007 |
| Grant date | Apr 16, 2013 |
| Priority date | — |
| Expiry date | Jun 30, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P39/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The current invention provides methods and compositions for treating sensorineural hearing loss including but not limited to acute acoustic trauma (AAT). The composition includes compounds which function as free radical traps such as phenyl butyl nitrone (PBN), free radical scavengers, such as edaravone, resveratrol, ebselen and iron chelator and compounds from the family of antioxidant compounds including, but not limited to, N-acetylcysteine (NAC), Acetyl-L-Carnitine (ALCAR), glutathione monoethylester, ebselen, D-methionine and carbamathione. The compositions of the current invention may be delivered by injections or orally.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.