6-substituted-2,3,4,5-tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonists
US8420631B2 · kind B2 · utility
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Key dates
| Filing date | Sep 1, 2006 |
| Grant date | Apr 16, 2013 |
| Priority date | — |
| Expiry date | Aug 2, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula (I) as selective 5-HT2C receptor agonists for the treatment of 5-HT2C associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety: where R6 is —C≡C—R10, —CH═CR11R11′, or —(C0-C8)alkyl-Ar2 optionally substituted on the alkyl moiety with 1 to 6 fluoro substituents and other substituents are as defined in the specification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.