4-benzylaminoquinolines, pharmaceutical compositions containing them, and their use in therapy

US8420670B2 · kind B2 · utility

Assignees

• Abbott Laboratories · US
• Abbott GmbH & Co. KG · DE

Inventors

• Wilhelm Amberg · Ludwigshafen, DE
• Michael Ochse · Wiesbaden, DE
• Wilfried Braje · Ludwigshafen, DE
• Berthold Behl · Ludwigshafen, DE
• Wilfried Hornberger · Wiesbaden, DE
• Mario Mezler · Ludwigshafen, DE
• Charles W. Hutchins · Libertyville, US

Key dates

• Filing date: Aug 22, 2008
• Grant date: Apr 16, 2013
• Expiry date: Aug 18, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to 4-benzylaminoquinolines of the formula (I) or physiologically tolerated salts thereof. The invention relates to pharmaceutical compositions comprising such quinolines, and the use of such quinolines for therapeutic purposes. The quinolines are GIyTI inhibitors.