Crystalline form of 4-[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]-amino]-2-pyrimidinyl]amino]benzonitrile

US8426434B2 · kind B2 · utility

Assignee

• Tibotec Pharmaceuticals Ltd. · IE

Inventors

• Sigrid Carl Maria Stokbroekx · Beerse, BE
• Carina Leys · Stabroek, BE
• Elisabeth Maria Hélène Egide Ghislaine Theunissen · Wilsele, BE
• Lieven Elvire Colette Baert · Brugge, BE

Key dates

• Filing date: Jul 11, 2008
• Grant date: Apr 23, 2013
• Expiry date: Jun 9, 2029

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention concerns polymorph I of TMC278, its use and preparation. It further concerns pharmaceutical formulations comprising this polymorph.