Patent · US Active

2′,2-bisthiazole non-nucleoside compounds, preparation methods, pharmaceutical compositions and uses as hepatitis virus inhibitors thereof

US8426606B2 · kind B2 · utility

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18Claims

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Assignee

SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES · CN

Inventors

Fajun Nan · Shanghai, CN
Jianping Zuo · Shanghai, CN
Yangming Zhang · Shanghai, CN
Wei Tang · Shanghai, CN

Key dates

Filing date	Mar 16, 2011
Grant date	Apr 23, 2013
Priority date	—
Expiry date	Mar 16, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P31/20
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure belongs to the field of pharmaceutical chemistry, and relates to a class of 2′,2-bisthiazole non-nucleoside compounds of following formula I, the preparation method and the pharmaceutical composition thereof. The compounds have both the anti-HBV and anti-HCV activities and are useful in treating hepatitides B and C. Pharmacokinetic tests showed the compounds have good bioavailability.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.