Nucleic acids and proteins from Streptococcus groups A and B

US8431139B2 · kind B2 · utility

Assignees

• Novartis Vaccines and Diagnostics, Inc. · US
• J. Craig Venter Institute, Inc. · US

Inventors

• John Telford · Colle di Val d'Elsa, IT
• Vega Masignani · Siena, IT
• Maria Scarselli · Siena, IT
• Guido Grandi · Segrate, IT
• Herve Tettelin · Rockville, US
• Claire Fraser · Centreville, US

Key dates

• Filing date: May 16, 2006
• Grant date: Apr 30, 2013
• Expiry date: Jul 27, 2026

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides proteins from group B streptococcus (Streptococcus agalactiae) and group A streptococcus (Streptococcus pyogenes), including amino acid sequences and the corresponding nucleotide sequences. Data are given to show that the proteins are useful antigens for vaccines, immunogenic compositions, and/or diagnostics. The proteins are also targets for antibiotics.