Topical compositions
US8431140B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 14, 2007 |
| Grant date | Apr 30, 2013 |
| Priority date | — |
| Expiry date | Jan 18, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Single phase pharmaceutical compositions for topical application, in addition to kits and methods of use and administration are provided. The compositions comprise a biologically active agent; a delivery vehicle comprising at least a non-polymeric crystallization inhibitor and a film-former; and a volatile solvent; wherein the biologically active agent is present in the composition in a subsaturated state, the biologically active agent is present in the delivery vehicle in a supersaturated state, and the crystallization inhibitor is capable of delaying crystallization of the biologically active agent in the delivery vehicle. Biologically active agents include terbinafine and acyclovir. Treatments for onychomycosis and Varicella zoster infection, HSV-I infection or HSV-2 infection are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.