Microparticles containing biodegradable polymer and cationic polysaccharide for use in immunogenic compositions
US8431160B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 24, 2007 |
| Grant date | Apr 30, 2013 |
| Priority date | — |
| Expiry date | Sep 24, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/6093
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Immunogenic compositions are described herein which comprise microparticles that further comprise a biodegradable polymer. The microparticle compositions also comprise a cationic polysaccharide and an immunological species selected from an antigen, an immunological adjuvant and a combination thereof. Also described are methods of making such compositions and methods of administering such compositions. Methods of modulating the release rate of immunological species from microparticles are also described. These methods comprise varying the ratio of the cationic polysaccharide relative to the biodegradable polymer within the microparticles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.