Method and apparatus for measuring analyte transport across barriers using x-ray fluorescence
US8431357B2 · kind B2 · utility
18Cited by
1References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 1, 2009 |
| Grant date | Apr 30, 2013 |
| Priority date | — |
| Expiry date | Oct 9, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2223/076
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention includes a method and apparatus for measuring the removal of analyte from a cell. One or more cells are provided, comprising at least 10 picograms of an analyte within a volume defined by the area of an x-ray excitation beam and a depth of a depth of five times the 1/e attenuation depth for at least one characteristic x-ray signal of the analyte as attenuated by water. At least a of portion of the analyte is removed from the cells; and the analyte is measured using x-ray fluorescence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.