HDAC inhibitors and therapeutic methods of using same

US8431538B2 · kind B2 · utility

Assignee

• The Board of Trustees of the University of Illinois · US

Inventors

• Alan P. Kozikowski · Princeton, US
• Kyle Butler · Stanford, US
• Jay H. Kalin · Chicago, US

Key dates

• Filing date: Jul 2, 2010
• Grant date: Apr 30, 2013
• Expiry date: Jul 2, 2030

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Histone deacetylases inhibitors (HDACIs) and compositions containing the same are disclosed. Methods of treating diseases and conditions wherein inhibition of HDAC provides a benefit, like a cancer, a neurodegenerative disorder, a neurological disease, traumatic brain injury, stroke, malaria, an autoimmune disease, autism, and inflammation, also are disclosed.