Patent · US Active

Capped pyrazinoylguanidine sodium channel blockers

US8431579B2 · kind B2 · utility

27Cited by

33References

19Claims

0Family size

Assignee

Parion Sciences, Inc. · US

Inventors

Michael R. Johnson · Chapel Hill, US
Bruce F. Molino · Slingerlands, US
Jianzhong Zhang · Plano, US
Bruce Sargent · Nottingham, GB

Key dates

Filing date	Nov 4, 2010
Grant date	Apr 30, 2013
Priority date	—
Expiry date	Nov 4, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D473/16
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided are compounds represented by the formula:where the structural variables are as defined herein. The compounds function as sodium channel blockers and my be used for promoting hydration of mucosal surfaces.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.