Heteroaryl amide derivatives

US8431593B2 · kind B2 · utility

Assignee

• H. LUNDBECK A/S · DK

Inventors

• Alan Hutchison · Madison, US
• Hongbin Li · Newtown, US
• Jianmin Mao · Winchester, US
• David Juergen Wustrow · Ann Arbor, US
• Jun Yuan · Guilford, US
• He Zhao · Madison, US

Key dates

• Filing date: Nov 27, 2007
• Grant date: Apr 30, 2013
• Expiry date: Sep 6, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Heteroaryl amide derivatives are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.