Patent · US Active

Quinoline or isoquinoline substituted P2X7 antagonists

US8431704B2 · kind B2 · utility

21Cited by
0References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 21, 2009
Grant dateApr 30, 2013
Priority date
Expiry dateFeb 12, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is related to novel compounds of formula (I) having P2X7 antagonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with P2X7 receptor activity in animals, in particular humans. (I).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.