Method for detecting BPA by surface enhanced Raman spectroscopy
US8432544B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 15, 2011 |
| Grant date | Apr 30, 2013 |
| Priority date | — |
| Expiry date | Feb 28, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/658
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A detection method of bisphenol A by the surface-enhanced Raman spectroscopy includes: soaking and extracting bisphenol A present in a sample with an organic solvent to form an extraction solution, adding methanol to the extraction solution to cause a polymer to precipitate from the extraction solution and leaving a filtrate behind, filtering and concentrating the filtrate, diluting the concentrated filtrate to volume with methanol, filtering the diluted filtrate through a filter with a pore size of 0.45 μm to obtain a pretreated sample; detecting bisphenol A present in the sample by Raman spectroscopy under an incident laser power of 100 to 300 mW, and a scan time of 2 to 20 seconds; mixing the pretreated sample with the colloidal gold in an appropriate ratio, followed by adjusting pH value, and then carrying out the detection of bisphenol A present in the sample by Raman spectroscopy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.