Self-destructing transdermal therapeutic system having improved functionality and efficacy

US8435219B2 · kind B2 · utility

Assignee

• LTS Lohmann Therapie-Systeme AG · DE

Inventors

• Stephan Maier · Wettingen, CH
• Margit Wirz · Polch, DE

Key dates

• Filing date: Mar 26, 2009
• Grant date: May 7, 2013
• Expiry date: Aug 20, 2029

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B09B2101/68
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a self-destructing transdermal therapeutic system (TTS), preferably in the form of a transdermal patch, that includes an active ingredient, an agent rendering the active ingredient useless, and a perforation mechanism. The perforation mechanism allows a mobile phase to reach an agent that is capable of rendering the active ingredient useless after removing the TTS after use. The agent then comes into contact with the active ingredient and destroys the active ingredient in the presence of the mobile phase.