Quantification method for remaining liver function and novel liver receptor imaging agent
US8435491B2 · kind B2 · utility
40Cited by
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2Claims
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Key dates
| Filing date | May 13, 2010 |
| Grant date | May 7, 2013 |
| Priority date | — |
| Expiry date | Oct 9, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K51/0497
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A test indicator for quantifying remaining liver function is provided. A novel liver receptor imaging agent with liver targeting property is utilized to develop a method for quantifying remaining liver function to serve as test indicator for judging the liver failure outcome in clinic, particularly for judging the necessity of liver transplantation for patients with liver failure or liver disease. The radioactivity uptake of the test indicator was negatively correlated with the extent of liver reserve. The cutoff value of liver reserve for liver transplantation is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.