Methods of modulating lipid concentrations in eukaryotic cells
US8435790B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Jul 24, 2009 |
| Grant date | May 7, 2013 |
| Priority date | — |
| Expiry date | Dec 21, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02E50/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is based on the discovery of a set of genes that are involved in lipid-droplet formation and regulation. Accordingly, the present invention provides methods of increasing or decreasing lipid concentrations in eukaryotic cells by decreasing or increasing expression of one of these genes. Increased lipid concentrations may be useful, for example, in the generation of biofuels. Decreased lipid concentration may be useful in the treatment of diseases characterized by excessive lipid storage. In addition, the invention provides methods of identifying markers of diseases characterized by excessive lipid storage.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.