Bicyclic traizole derivatives for treating of tumors

US8435986B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Frank Stieber · Heidelberg, DE
• Oliver Schadt · Rodenbach, DE
• Dieter Dorsch · Ober-Ramstadt, DE
• Andree Blaukat · Heilbad Heiligenstadt, DE

Key dates

• Filing date: Jul 16, 2009
• Grant date: May 7, 2013
• Expiry date: Dec 25, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D403/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula (I), in which X1, X2, X3, X4, X5, R1, R2, R3, R3′, R4, R6 and R7 have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.