Serine protease derivatives and uses in the prevention or the treatment of blood coagulation disorders
US8436144B2 · kind B2 · utility
6Cited by
0References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 21, 2009 |
| Grant date | May 7, 2013 |
| Priority date | — |
| Expiry date | Dec 21, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/21069
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to chimeric derivatives of serine protease zymogen containing the activation peptide of factor X or a fragment thereof for improving the half-life of said derivatives. Preferably, said chimeric derivatives are protein C and factor X derivatives. The invention also relates to said derivatives for the prevention or treatment of blood coagulation disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.