Patent · US Active

Non-anaphylactic forms of grass pollen Ph1 p 6 allergen and their use

US8440200B2 · kind B2 · utility

0Cited by

1References

11Claims

0Family size

Assignee

PHADIA AB · SE

Inventors

Rudolf Valenta · Theresienfeld, AT
Susanne Vrtala · Wien, AT
Sabine Stumvoll · Spittal an der Drau, AT
Hans Grönlund · Lidingö, SE
Monika Grote · Hachenburg, DE
Luca Vangelista · Padova, IT
Annalisa Pastore · London, GB
Wolfgang Sperr · Wien, AT
Peter Valent · Wien, AT
Dietrich Kraft · Wien, AT

Key dates

Filing date	Nov 1, 2007
Grant date	May 14, 2013
Priority date	—
Expiry date	Aug 14, 2030

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S530/868
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Methods for desensitization of a mammal suffering from IgE mediated allergy comprise the steps of: administering to said mammal a therapeutically effective amount of an immunogenic and hypoallergenic composition which comprises (i) a Phl p 6 molecule having an N-terminal truncation which makes the molecule at least lack IgE binding capacity, and/or (ii) a Phl p 6 molecule having a C-terminal truncation which makes the molecule at least lack IgE binding capacity, wherein the molecules of (i) and (ii), if employed in combination, together span the complete sequence of Phl p 6, and a pharmaceutically acceptable carrier.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.