Swellable particles for drug delivery
US8440231B2 · kind B2 · utility
56Cited by
1References
21Claims
0Family size
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Key dates
| Filing date | Aug 31, 2012 |
| Grant date | May 14, 2013 |
| Priority date | — |
| Expiry date | Aug 31, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2982
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Swellable particles for delivery of a drug or other working agent to the pulmonary system are provided. The swellable particles include a dehydrated (dry) aerodynamic particle diameter of 5 μm or less to enable delivery to the respiratory tract, such as for example to the tracheo-bronchial airways of the upper respiratory tract and/or to the alveolic regions of the deep lung, and a hydrated particle diameter that is greater than 6 μm volume mean diameter to retard or prevent their phagocytosis by the macrophages present in airways of the respiratory tract.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.