Patent · US Active

Constitutively activated human G protein coupled receptors

US8440391B2 · kind B2 · utility

0Cited by

12References

20Claims

0Family size

Assignee

Arena Pharmaceuticals, Inc. · US

Inventors

Ruoping Chen · San Diego, US
Chen Liaw · San Diego, US
Kevin Lowitz · San Diego, US
Derek T. Chalmers · Solana Beach, US
Dominic P. Behan · San Diego, US

Key dates

Filing date	Nov 26, 2003
Grant date	May 14, 2013
Priority date	—
Expiry date	Aug 5, 2029

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor for which the endogenous ligand is unknown (“orphan GPCR receptors”), and most particularly to mutated (non-endogenous) versions of the human GPCRs for evidence of constitutive activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.