Patent · US Active

MST1 kinase inhibitors and methods of their use

US8440652B2 · kind B2 · utility

1Cited by

1References

17Claims

0Family size

Assignee

LEXICON PHARMACEUTICALS, INC. · US

Inventors

David J. Augeri · Princeton, US
Jeffrey Bagdanoff · Lawrence, US
Simon David Peter Baugh · Ringoes, US
Marianne Carlsen · Yardley, US
Kenneth G. Carson · Princeton, US
John A. Gilleran · New Brunswick, US
Wei He · Audubon, US
Tamas Oravecz · Diemelstraße, US
Konstantin Salojin · Conroe, US
Leonard Sung · San Mateo, US

Key dates

Filing date	Mar 2, 2012
Grant date	May 14, 2013
Priority date	—
Expiry date	Mar 2, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D495/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds for the inhibition of mammalian Ste20-like kinase 1 (MST1) are disclosed, along with compositions comprising them and methods of their use in the treatment, management or prevention of an inflammatory or autoimmune diseases or disorders. Particular compounds are of the formula:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.