Patent · US Active

Trisubstituted 1,2,4 triazoles

US8440701B2 · kind B2 · utility

0Cited by

4References

8Claims

0Family size

Assignee

Janssen Pharmaceuticals, Inc. · BE

Inventors

Johannes Wilhelmus John F. Thuring · Ekeren, BE
Theodorus Dinklo · Beerse, BE
Anne Simone Josephine Lesage · Zoersel, BE
Marcel Frans Leopold De Bruyn · Wortel, BE
Wei Zhuang · Monheim, DE

Key dates

Filing date	Oct 15, 2008
Grant date	May 14, 2013
Priority date	—
Expiry date	Feb 8, 2029

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to substituted 1-(alkyl)-3-aniline-5-aryl triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I).The invention particularly relates to potent positive allosteric modulators of nicotinic acetylcholine receptors which have the capability of increasing the efficacy of nicotinic receptor agonists.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.