Compounds, compositions and methods of inhibiting alpha-synuclein toxicity
US8440705B2 · kind B2 · utility
7Cited by
61References
18Claims
0Family size
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Key dates
| Filing date | Sep 16, 2005 |
| Grant date | May 14, 2013 |
| Priority date | — |
| Expiry date | Mar 23, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds and compositions are provided for treatment or amelioration of one or more symptoms of α-synuclein toxicity, α-synuclein mediated diseases or diseases in which α-synuclein fibrils are a symptom or cause of the disease. In one embodiment, the compounds for use in the compositions and methods are heteroaryl acylguanidines, heteroarylhydrazones, dihydropyridones, heteroaryl and aryl styryl ketones, and heteroarylpyrazoles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.