Patent · US Active

Biological and chemical microscopic targeting

US8441632B2 · kind B2 · utility

2Cited by
6References
22Claims
0Family size

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Inventor

Key dates

Filing dateAug 25, 2010
Grant dateMay 14, 2013
Priority date—
Expiry dateMay 28, 2031

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2021/656
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Biological and chemical materials often contain many molecular bonds that connect carbon (C) hydrogen (H) atoms. These bonds covalently share electrons that can be optically activated by light. The incident light interaction with the C—H molecular bond spectrally shifts of the incident light proportional to the vibrational, or more precisely polarizability, constant of the electrons that bind the C—H atoms. This process is called Raman scattering. For C—H, C—H2 and C—H3 bonding schemes, the spectral shift is approximately 3000 cm−1 lower in energy from the incident light energy. Using this fundamental spectral shift coupled with optical microscopy, the ability to detect materials that possess C—Hx (where x=1, 2 or 3) is possible.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.