Patent · US Active

Antigen binding polypeptides

US8444976B2 · kind B2 · utility

12Cited by

2References

19Claims

0Family size

Assignee

argenx BV · BE

Inventors

Torsten Dreier · Breda, NL
Christophe Blanchetot · Laarne, BE
Johannes Joseph Wilhelmus De Haard · Vlaardingen, NL

Key dates

Filing date	Jul 2, 2009
Grant date	May 21, 2013
Priority date	—
Expiry date	Jun 10, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/158
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to a platform technology for production of antigen binding polypeptides having specificity for a desired target antigen which is based on the conventional antibody repertoire of species in the family Camelidae, and to antigen binding polypeptides obtained using this technology platform. In particular, the invention provides an antigen binding polypeptide comprising a VH domain and a VL domain, wherein at least one hypervariable loop or complementarity determining region (CDR) in the VH domain or the VL domain is obtained from a VH or VL domain of a species in the family Camelidae.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.