Peptides protective against S. pneumoniae and compositions, methods and uses relating thereto

US8445001B2 · kind B2 · utility

Assignee

• Intercell AG · AT

Inventors

• Andreas Meinke · Pressbaum, AT
• Astrid Teubenbacher · Wien, AT
• Beatrice Tschanun · Wien, AT
• Manuel Zerbs · Wien, AT
• Markus Hanner · Pressbaum, AT
• Jutta Pikalo · Strau, AT
• Eszter Nagy · Wien, AT
• Carmen Giefing · Sieggraben, AT
• Alexander Von Gabain · Wien, AT

Key dates

• Filing date: Aug 3, 2012
• Grant date: May 21, 2013
• Expiry date: Aug 3, 2032

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2469/20
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a protective peptide of Streptococcus pneumoniae (S. pneumoniae) or a functionally active variant thereof; a composition comprising at least two of such peptides or variants; one or more nucleic acid(s) encoding such peptide or variant; a pharmaceutical composition comprising such peptide or variant, composition, or nucleic acid(s); a method of producing an antibody using such peptide or variant or composition; the use of such peptide or variant and/or composition and/or nucleic acid(s) for the manufacture of a medicament; a method of diagnosing a S. pneumoniae infection using such peptide or variant, composition or a primer and/or probe specific for the nucleic acid(s); a method for identifying a ligand capable of binding to such peptide or variant; and the use of such peptide or variant for the isolation, purification and/or identification of an interaction partner of the peptide.