Patent · US Active

Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and prostamide

US8445027B2 · kind B2 · utility

24Cited by
128References
11Claims
0Family size

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Inventors

Key dates

Filing dateJun 3, 2011
Grant dateMay 21, 2013
Priority date
Expiry dateJun 3, 2031

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01J13/06
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Biocompatible intraocular implants, such as microparticles, include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide component into an eye for an extended period of time. The prostamide component may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the prostamide component may be encapsulated by the polymeric component. The present implants include oil-in-oil emulsified implants or microparticles. Methods of producing the present implants are also described. The implants may be placed in an eye to treat or reduce at least one symptom of an ocular condition, such as glaucoma.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.