Processes and kits for determining multi-drug resistance of cells
US8445271B2 · kind B2 · utility
6Cited by
0References
54Claims
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Assignee
Inventors
Key dates
| Filing date | May 3, 2010 |
| Grant date | May 21, 2013 |
| Priority date | — |
| Expiry date | Dec 29, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/44
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention relates to multi-drug resistance (MDR) in cells, and the use of certain xanthene compounds for determining drug resistance in cells and the effect of test compounds on cell membrane transport by the membrane transporters MDR1, MRP and BCRP. Processes and kits for making these determinations and measuring these effects are described and provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.