TGR5 modulators and methods of use thereof
US8445472B2 · kind B2 · utility
3Cited by
13References
11Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 7, 2011 |
| Grant date | May 21, 2013 |
| Priority date | — |
| Expiry date | Dec 7, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J41/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to compounds of Formula A:or a salt, solvate, hydrate, or prodrug thereof. The compounds of Formula A are TGR5 modulators useful for the treatment of various diseases, including metabolic disease, inflammatory disease, liver disease, autoimmune disease, cardiac disease, kidney disease, cancer, and gastrointestinal disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.