Patent · US Active

Hydrazonopyrazole derivatives and their use as therapeutics

US8445694B2 · kind B2 · utility

0Cited by
4References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 23, 2010
Grant dateMay 21, 2013
Priority date
Expiry dateDec 23, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Pharmaceutical compositions and compounds are provided. The compounds of the invention demonstrate anti-proliferative activity, and may promote apoptosis in cells lacking normal regulation of cell cycle and death. In one embodiment of the invention, pharmaceutical compositions of the compounds in combination with a physiologically acceptable carrier are provided. The pharmaceutical compositions are useful in the treatment of hyperproliferative disorders, which disorders include tumor growth, lymphoproliferative diseases, angiogenesis. The compounds of the invention are substituted pyrazoles and pyrazolines.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.