Methods for using a stent having nanoporous layers

US8449602B2 · kind B2 · utility

Assignee

• Medtronic Vascular, Inc. · US

Inventors

• Whye-Kei Lye · Charlottesville, US
• Gary Owens · Earlysville, US
• Brian R. Wamhoff · Charlottesville, US
• Matthew Hudson · Charlottesville, US
• Joshua Spradlin · Charlottesville, US
• Kareen Looi · Charlottesville, US

Key dates

• Filing date: Feb 10, 2006
• Grant date: May 28, 2013
• Expiry date: Feb 14, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61N1/05
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Implantable medical devices having at least one porous layer, and methods for making such devices, and loading such devices with therapeutic agents are described. A mixture or alloy is placed on the surface of a medical device, then one component of the mixture or alloy is generally removed without generally removing the other components of the mixture or alloy to create the pores of the porous layer. The porous layer may be adapted for bonding non-metallic coating, including drug eluting polymeric coatings. A porous layer may have a random pore structure or an oriented or directional grain porous structure. The medical device may be a vascular stent having at least one porous layer adapted to resist stenosis or cellular proliferation.