Microfluidic device for high-throughput cellular gradient and dose response studies
US8449837B2 · kind B2 · utility
2Cited by
49References
23Claims
0Family size
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Key dates
| Filing date | Oct 11, 2006 |
| Grant date | May 28, 2013 |
| Priority date | — |
| Expiry date | Feb 20, 2029 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/082
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The ability to form and maintain gradients is essential for the study of response of cells to various stimuli. The invention includes devices and methods for the high-throughput, reproducible formation of gradients for the study of living cells. The invention includes microfluidics device with a test chamber having a depth flanked by flow-through channels having a deeper depth. Flow of two different fluids through the flow-through channels results in the creation of a gradient by diffusion across the test chamber having essentially no flow.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.