Protein-proteophore complexes

US8450097B2 · kind B2 · utility

Assignee

• Ascendis Pharma Inc. · DE

Inventors

• Dirk Vetter · Heidelberg, DE
• Ulrich Hersel · Heidelberg, DE
• Harald Rau · Würzburg, DE
• Robert Schnepf · Dossenheim, DE
• Thomas Wegge · Heidelberg, DE

Key dates

• Filing date: Dec 14, 2010
• Grant date: May 28, 2013
• Expiry date: Dec 14, 2030

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S977/754
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The application relates to a composition comprising a hyperbranched polymer attached to a core and a biologically active moiety. The biologically active moiety is attached to the core by means of a substantially non-enzymatically cleavable linker L. The composition can be used to deliver the biologically active moiety to its target.