Patent · US Active

Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds

US8450344B2 · kind B2 · utility

45Cited by
17References
37Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 25, 2008
Grant dateMay 28, 2013
Priority date
Expiry dateFeb 5, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are beta and gamma-amino isoquinoline amide compounds and substituted benzamide compounds. In particular, the invention provides compounds that affect the function of kinases in a cell and that are useful as therapeutic agents or with therapeutic agents. The compounds of the invention are useful in the treatment of a variety of diseases and conditions including eye diseases such as glaucoma, cardiovascular diseases, and diseases characterized by abnormal growth, such as cancers. The invention further provides compositions containing the beta or gamma-amino isoquinoline amide compounds or substituted benzamide compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.