Triazoles as inhibitors of fatty acid synthase
US8450350B2 · kind B2 · utility
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47References
37Claims
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Key dates
| Filing date | May 5, 2011 |
| Grant date | May 28, 2013 |
| Priority date | — |
| Expiry date | Aug 31, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are triazole FASN inhibitors of the formula (I):or a pharmaceutically acceptable form thereof; wherein the variables RA, X, RB, and RC are defined herein.Also provided herein are pharmaceutical compositions of the compounds provided herein as well as methods of their use for the treatment of various disorders such as hyperproliferative disorders, inflammatory disorders, obesity-related disorders and microbial infections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.