ABCB5 positive mesenchymal stem cells as immunomodulators
US8455245B2 · kind B2 · utility
12Cited by
14References
10Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 31, 2007 |
| Grant date | Jun 4, 2013 |
| Priority date | — |
| Expiry date | Jun 26, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N5/0668
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to purified preparations of dermal mesenchymal stem cells that are characterized by the cell surface expression of the ABCB5 P-glycoprotein. The cells may be used for any purpose that mesenchymal stem cells from other course are used. For instance they may be administered to treat an organ transplant recipient to improve allograft survival or as a treatment to patients with autoimmune diseases such as multiple sclerosis and rheumatoid arthritis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.