Antidotes for factor Xa inhibitors and methods of using the same in combination with blood coagulating agents
US8455439B2 · kind B2 · utility
22Cited by
20References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 11, 2009 |
| Grant date | Jun 4, 2013 |
| Priority date | — |
| Expiry date | Jul 17, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P7/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to antidotes of anticoagulants targeting factor Xa which antidotes are used in combination with blood coagulating agents or other heparin antidotes to prevent or reduce bleeding in a subject. The antidotes described herein have reduced or no intrinsic coagulant activity. Disclosed herein are methods of stopping or preventing bleeding in a patient that is or will be undergoing anticoagulant therapy with a factor Xa inhibitor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.