Patent · US Active

Modified therapeutic agents

US8455447B2 · kind B2 · utility

0Cited by

3References

28Claims

0Family size

Assignee

Adprotech Limited · GB

Inventors

Dirk Esser · Cambridge, GB
Jason Richard Betley · Stowmarket, GB
Simon Ridley · Cambridge, GB

Key dates

Filing date	Jan 15, 2010
Grant date	Jun 4, 2013
Priority date	—
Expiry date	Sep 6, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K7/08
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention provides a modified therapeutic agent, said modified agent comprising three or more membrane binding elements with low membrane affinity covalently associated with the agent which elements are capable of interacting independently and with thermodynamic additivity, with components of cellular or artificial membranes exposed to extracellular fluids wherein at least two membrane binding elements are lipophilic elements, which may be aliphatic acyl groups, which may be selected from the list consisting of Myristoyl, Decanoyl or Hexanoyl.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.