Heterocyclic compounds

US8455479B2 · kind B2 · utility

Assignee

• PANACEA BIOTEC LIMITED · IN

Inventors

• Rajesh Jain · New Delhi, IN
• Sanjay Trehan · Hyderabad, IN
• Jagattaran Das · New Delhi, IN
• Nishan Singh · New Delhi, IN
• Gurmeet Kaur Nanda · New Delhi, IN
• Sitaram Kumar Magadi · Hyderabad, IN
• Sudhir Kumar Sharma · New Delhi, IN

Key dates

• Filing date: Jan 23, 2009
• Grant date: Jun 4, 2013
• Expiry date: Jul 1, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel compounds of Formula I, their pharmaceutically acceptable derivatives, tautomeric forms, stereoisomers including R and S isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of Formula I, their pharmaceutically acceptable derivatives, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions comprising compounds of Formula I and methods of treating or preventing one or more conditions that may be regulated or normalized via inhibition of dipeptidyl peptidase IV (DPP-IV).