Patent · US Active

Cytokine concentration system

US8460227B2 · kind B2 · utility

10Cited by
2References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 10, 2009
Grant dateJun 11, 2013
Priority date—
Expiry dateMay 1, 2031

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01L3/5021
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Apparatus and methods for producing interleukin-1 receptor antagonist and/or other prophylatically or therapeutically effective protein. Blood is obtained from a patient with a conventional syringe and then introduced into dual luer lock centrifuge tube. The dual luer lock centrifuge tube is provided with beads that are coated with a silanized coating. The container is then incubated and centrifuged. Subsequent to the incubation and the centrifugation, the serum containing autologous therapeutically active protein, such as IL-1Ra, in the container is withdrawn through the luer lock of the container, and injected back into the patient.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.