Patent · US Active

Reconstitutable microsphere compositions useful as ultrasonic contrast agents

US8460637B2 · kind B2 · utility

1Cited by

16References

7Claims

0Family size

Assignee

University of Pittsburgh—Of the Commonwealth System of Higher Education · US

Inventors

Thomas B. Ottoboni · Belmont, US
Robert E. Short · Los Gatos, US

Key dates

Filing date	Oct 4, 2011
Grant date	Jun 11, 2013
Priority date	—
Expiry date	Oct 4, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K49/225
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Methods and suspensions are provided that are useful for preparing readily reconstitutable, dry compositions of micro- or nanospheres. The dry compositions find use in diagnostic applications such as ultrasonic imaging. The suspension includes as key ingredients one or both of t-butyl alcohol and/or an amorphous sugar (or mixture of amorphous sugar) in specified amounts that reduce aggregation of the particles comprising the suspension.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.