LOX and LOXL2 inhibitors and uses thereof
US8461303B2 · kind B2 · utility
16Cited by
68References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 1, 2008 |
| Grant date | Jun 11, 2013 |
| Priority date | — |
| Expiry date | Sep 29, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/90633
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application relates to anti-LOX and anti-LOXL2 antibodies and their use in purification, diagnostic and therapeutic methods. Antibodies include monoclonal antibodies, humanized antibodies and functional fragments thereof. Anti-LOX and anti-LOXL2 antibodies can be used to identify and treat conditions such as a fibrotic condition, angiogenesis, or to prevent a transition from an epithelial cell state to a mesenchymal cell state.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.