Aptamers to tissue factor pathway inhibitor and their use as bleeding disorder thereapeutics
US8461318B2 · kind B2 · utility
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11References
1Claims
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Key dates
| Filing date | Nov 3, 2011 |
| Grant date | Jun 11, 2013 |
| Priority date | — |
| Expiry date | Nov 3, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P7/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates generally to the field of nucleic acids and more particularly to aptamers that bind to TFPI, which are useful as therapeutics in and diagnostics of bleeding disorders and/or other diseases or disorders in which TFPI has been implicated. In addition, the TFPI aptamers may be used before, during and/or after medical procedures to reduce complications or side effects thereof. The invention further relates to materials and methods for the administration of aptamers that bind to TFPI.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.