Nucleic acids encoding a deletion variant of uPAR

US8461321B2 · kind B2 · utility

Assignee

• Wilex AG · DE

Inventors

• Thomas E. Luther · Santa Clara, US
• Viktor Magdolen · Tauberbischofsheim, DE
• Manfred Schmitt · Munich, DE
• Bernd Muehlenweg · Munich, DE
• Matthias Kotzsch · Dresden, DE

Key dates

• Filing date: Jun 30, 2008
• Grant date: Jun 11, 2013
• Expiry date: Oct 19, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/34
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to the production of specific antibodies for the detection of human tumor associated urokinase-type plasminogen activator receptor (uPAR) deletion variants in biological samples as well as to their diagnostic and therapeutic application.