Methods and apparatus for fabricating porous 3-dimensional cell culture construct for cell culture and other biomedical applications
US8463418B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 18, 2008 |
| Grant date | Jun 11, 2013 |
| Priority date | — |
| Expiry date | Jul 23, 2029 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB29K2105/04
- WIPO fieldOther special machines
- WIPO sectorMechanical engineering
Abstract
The present invention provides an RP system which can directly use hot melt polymers for fabricating porous 3D construct for cell culture and other biomedical applications based on a CAD design. To realize the direct use of polymer hot melt, the RP system uses a hot melt chamber which is mounted on a robotic dispensing ann or a XYZ motion control system. The hot melt chamber is equipped with a delivery mechanism to force the molten polymer passing through a nozzle. The extruded polymer thin filament deposits onto the positions according to the computer generated model, in a layer-by-layer fashion, similar to FDM. The present invention can use any type of thennal plastic polymer pellets, beads, particles, which are suitable for extrusion and injection molding, as well as composites of two or more different thermal plastic polymer blends, inorganic particle/thennal plastic composites.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.