Irreversible electroporation using nanoparticles
US8465484B2 · kind B2 · utility
112Cited by
111References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 30, 2009 |
| Grant date | Jun 18, 2013 |
| Priority date | — |
| Expiry date | Mar 2, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/05
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) to cause cell death in treated tumors. In embodiments, the methods comprise the use of high aspect ratio nanoparticles with or without modified surface chemistry.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.