Method of making tyrosine kinase microspheres
US8465778B2 · kind B2 · utility
31Cited by
137References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 19, 2012 |
| Grant date | Jun 18, 2013 |
| Priority date | — |
| Expiry date | Jun 19, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2985
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Biocompatible intraocular microspheres include a tyrosine kinase inhibitor and a biodegradable polymer that is effective to facilitate release of the tyrosine kinase inhibitor into the vitreous of an eye for an extended period of time. The therapeutic agents of the microspheres can be associated with a biodegradable polymer matrix, such as a matrix that is substantially free of a polyvinyl alcohol. The microspheres can be placed into an eye to treat or reduce the occurrence of one or more ocular conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.