Patent · US Active

Markers for diagnosis of pulmonary inflammation and methods related thereto

US8465923B2 · kind B2 · utility

5Cited by
1References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 16, 2011
Grant dateJun 18, 2013
Priority date—
Expiry dateDec 16, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q2600/158
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA 112, CSPG2, TLR2, and CD163.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.